基于Coriolus versicolor的阴道凝治疗与HPV相关的宫疾病的临床证据:叙述性综述

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Emmanuel Sánchez Díaz¹, Gabriel Levin², Andreina Fernandes³

¹Department of Gynecologic Oncology, Instituto Nacional de Cancerología, Bogotá, Colombia.

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概括

本综述研究了一种多成分的阴道凝,用于治疗人类乳头瘤病毒 (HPV) 感染和低度宫发育不良. 目前的证据不足以用于常规使用,需要对HPV清除和病变管理进行更严格的试验.

科学领域:

妇科妇科医生妇科
传染性疾病传染性疾病
在瘤学瘤学.

背景情况:

人类乳头瘤病毒 (HPV) 感染是一种常见的性传播疾病,有可能导致宫癌.
没有批准的治疗方法专门针对HPV感染或低度状内皮病变 (LSILs).
一种新型的多成分阴道凝旨在支持HPV清除并促进病变愈合.

研究的目的:

审查和批判性地分析关于HPV感染和宫低度形的多成分阴道凝的现有证据.
总结评估凝的研究的临床结果,优点和局限性.

主要方法:

在主要数据库 (MEDLINE,Embase,Scopus) 进行了系统的文献搜索.
额外的记录来自临床试验.gov和谷歌学者.
包括同行评审的出版物和会议摘要关于基于Trametes versicolor的阴道凝 (Papilocare®/Palomacare®).

主要成果:

该审查涵盖了试点研究,前性非对照性试验,随机临床试验和回顾性观察性研究的证据.
初步数据表明,在上皮质修复和HPV清除方面存在潜在的益处.
指出了方法上的局限性,包括缺乏盲目和活检确认.

结论:

目前的证据不足以推阴道凝的常规临床使用.
需要进一步独立,精心设计和充足的随机试验.
加强的方法严谨性对于确定凝在管理与HPV相关的宫疾病中的作用至关重要.

关键词:

这就是为什么Trametes Trametes.宫内皮质瘤 (CIN) 发生在宫上.补充疗法补充疗法乳头瘤病毒感染的感染阴道奶油,泡和果.

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