一个脏移植接受者患有带状疹和死性细菌超级感染:一个病例报告
Anna Garstenauer1, Raffael Scharinger2, Christof Aigner1
1Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Frontiers in medicine
|March 9, 2026
概括
一名脏移植患者患上了一种罕见的,危及生命的皮肤感染,这种皮肤感染是由Pseudomonas aeruginosa引起的,这是由于varicella zoster病毒. 及时的美罗胺治疗导致了恢复,但有剩余的面部神经麻.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 皮肤病学 皮肤病学
背景情况:
- 初级疹病毒 (VZV) 感染是移植接受者的已知并发症.
- 免疫受损的个体容易受到严重的细菌感染.
- Pseudomonas aeruginosa 可以导致严重的死性皮肤和软组织感染 (SSTI).
研究的目的:
- 报告一个罕见的单微生物死性SSTI病例,由Pseudomonas aeruginosa引起,发生在接受脏移植的人身上.
- 突出VZV感染在免疫受损患者的潜在并发症.
- 讨论这种严重感染的管理和结果.
主要方法:
- 一个45岁的脏移植接受者的病例报告.
- 记录了临床表现,诊断工作 (血液和伤口培养) 以及治疗干预措施.
- 监测了患者的临床过程,治疗反应和长期后果.
主要成果:
- 该患者出现了VZV感染并发症,由Pseudomonas aeruginosa诱导的死性SSTI.
- 由于面部和口腔胀导致的气道损害,需要进行内内管道输入.
- 向的美罗胺疗法导致临床改善,保留了全移植功能,并恢复,尽管有剩余的面部神经麻.
结论:
- 与 Pseudomonas aeruginosa 相关的单微生物死性SSTI 很少见,但危及生命,特别是在免疫性受损的宿主中.
- 早期诊断和向的抗微生物治疗对于管理这些严重感染至关重要.
- VZV感染可能使移植接受者易患严重的二次细菌并发症.
相关概念视频
01:26Kidney Transplant II: Surgical Procedure
628
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
628
01:28Kidney Transplant I: Introduction
615
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
615
01:16Kidney Transplant III: Nursing Management
472
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
472
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
573
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
573
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
434
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
434
01:29Acute Kidney Injury III: Clinical Manifestations
1.2K
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
1.2K