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Updated: Mar 10, 2026

Investigating Mast Cell Secretory Granules; from Biosynthesis to Exocytosis
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Published on: January 26, 2015

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外源基胺酶调解MSC衍生的EV生物发生,并通过重新包装分子载荷来增强功效

Daniel C Shah1,2, S'Dravious A DeVeaux1,2, Hongmanlin Zhang2,3

  • 1The Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech and Emory, Atlanta, GA, USA.

iScience
|March 9, 2026
PubMed
概括

用基米林酶 (SMase) 酶化修改中基细胞 stromal cell (MSC) 细胞外囊泡 (EVs),提高了它们的治疗潜力. 用SMase处理的EV显示出更好的产量和更改的载荷,促进伤口愈合和血管生成的再生和免疫调节功能.

关键词:
生物化学 生物化学细胞生物学 细胞生物学分子生物学分子生物学

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