在患有急性脑梗塞的老年患者中,虚弱和认知障碍之间的关联
Xiangjun Tao1, Ying Wang2, Shu Ding1
1Department of Nursing, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Frontiers in aging neuroscience
|March 9, 2026
概括
住院治疗急性脑梗塞的老年患者往往会经历认知障碍. 这项研究发现,较高的脆弱性和酒精摄入量是这些患者认知障碍的独立预测因素.
科学领域:
- 老年学是一门学科.
- 神经学 神经学
- 认知科学 认知科学
背景情况:
- 脑卒中后的认知障碍在老年人中很普遍.
- 在中风后,虚弱和认知功能之间的相互作用需要进一步调查.
- 在急性脑梗塞住院期间对多维脆弱性评估的数据有限.
研究的目的:
- 研究因急性脑梗塞住院的老年患者的虚弱和认知障碍之间的关联.
- 探索虚弱的领域级认知相关性.
- 在这个人群中识别认知障碍的预测因素.
主要方法:
- 一项横截面研究纳入了179名因急性脑梗塞住院的65岁以上的患者.
- 使用埃德蒙顿脆弱度量 (EFS) 评估脆弱性,使用蒙特利尔认知评估 (MoCA) 评估认知能力.
- 多变量逻辑回归确定了认知障碍 (CI) 的预测因素,定义为MoCA <26.
主要成果:
- 认知障碍 (CI) 在65.4%的参与者中存在.
- 较高的脆弱性得分 (EFS ≥6) 在CI组中更为普遍 (59.8%与19.4%相比).
- 虚弱度评分 (OR 1.34) 和酒精摄入量 (OR 1.43) 独立与CI相关;高等教育具有保护性 (OR 0.59).
结论:
- 老年中风患者的认知障碍与脆弱性和酒精消费增加有关.
- 对于中风患者,建议在医院早期评估脆弱性和酒精摄入量.
- 研究结果强调,需要采用综合方法来管理中风后的认知衰退.
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