Aspergillus oryzae 在接受腹腔透析的患者的腹腔炎
Geng-Hao Bai1, Pao-Yu Chen2, Yu-Tsung Huang3
1Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Kidney medicine
|March 9, 2026
概括
一个罕见的Aspergillus oryzae腹膜炎病例使腹膜透析复杂化. 早期诊断使用 galactomannan 抗原测试和 voriconazole 治疗改善了患者的治疗结果,强调了考虑真菌病原体的重要性.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 菌类学 菌类学是指菌类学.
- 传染性疾病 传染性疾病
背景情况:
- 真菌腹膜炎是腹膜透析 (PD) 的严重并发症,通常与高发病率和死亡率有关.
- 虽然Candida物种很常见,但Aspergillus膜炎较为罕见,但经常致命.
- 这个病例涉及Aspergillus oryzae,这是PD患者真菌腹膜炎的不太常见原因.
研究的目的:
- 在接受连续门诊腹腔透析 (CAPD) 的患者中报告一种罕见的Aspergillus oryzae腹腔炎病例.
- 强调非培养生物标志物的诊断效用,如银河.
- 突出及时抗真菌治疗对于改善耐火性周周炎的结果的重要性.
主要方法:
- 一个54岁的男性CAPD患者的病例报告,患有糖尿病末期病.
- 临床表现包括的透析液,高C反应蛋白和腹白细胞增加.
- 诊断得到了阳性血清银曼南抗原测试的帮助,并通过PCR识别Aspergillus oryzae进行确认.
主要成果:
- 患者最初接受了经验性抗生素和可纳,但没有改善.
- 在阳性银河曼南测试后开始服用沃里康纳,导致症状改善.
- 克霍夫导管被移除,患者被转移到血液透析.
结论:
- 这是第二个报告的CAPD相关的Aspergillus oryzae腹膜炎病例.
- 早期考虑真菌病原体对于耐火性周周炎至关重要.
- galaktomannan 测试有助于快速诊断和及时的抗真菌治疗,改善患者的预后.
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