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转录组分析揭示了自闭症谱系障碍中的突触失调和线粒体功能障碍

Xiaoli Liao1,2, Jingqi Shao2, Zhihui Chen3

  • 1Hunan Provincial People's Hospital, Changsha, Hunan, China.

Brain, behavior, & immunity - health
|March 9, 2026
PubMed
概括

自闭症谱系障碍 (ASD) 显示了改变的基因表达,将线粒体功能障碍和突触问题联系起来. 这项研究揭示了一种分子特征,连接了ASD中的代谢干扰和突触异常,提供了潜在的治疗点.

关键词:
自闭症谱系障碍 自闭症谱系障碍线粒体功能障碍 线粒体功能障碍路径分析 路径分析突触失调的调节问题转录形状分析 (Transcriptomic Profiling) 是一种方法,可以进行转录形状分析.

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