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Updated: Mar 10, 2026

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
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异位CD11c驱动SMAD3介导的异常抗原呈现和上皮-半神经过渡在食道状细胞癌中

Han Liao1, Xuan Zhao1, Liping Chen1

  • 1Department of Etiology and Carcinogenesis, National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, P. R. China.

Cancer communications (London, England)
|March 9, 2026
PubMed
概括

在食道状细胞癌 (ESCC) 中异位CD11c表达通过激活SMAD3通路来驱动免疫逃避和恶性瘤. 针对这种CD11c-SMAD3轴可能会改善ESCC患者的免疫治疗疗效.

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