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Updated: Mar 10, 2026

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes
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家庭性高胆固醇血症的生物化学表征:遗传和脂质特征之间的关联

Lukač Sandra Singh1, Vladimir Gašić2, Jovana Komazec2

  • 1University Clinical Centre of Serbia, Clinic for Endocrinology, Diabetes and Metabolic Disease, Department for Lipid Disorders and Cardiovascular Complications in Diabetes, Belgrade, Serbia.

Journal of medical biochemistry
|March 9, 2026
PubMed
概括

这项关于塞尔维亚家族高胆固醇血症 (FH) 的研究发现,FH的遗传确认与更高的ApoB水平有关. 患有FH遗传变异的患者在接受治疗后不太可能达到目标LDL-C水平.

关键词:
家庭性高胆固醇血症是什么?遗传学 遗传学 遗传学 是一个脂质新陈代谢 脂质新陈代谢目标的LDL-C水平.

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