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在扩散大B细胞淋巴瘤中对CAR-T细胞治疗的耐药性机制的研究进展

Shuran Zhang1, Jiye Liu1, Zengjun Li1

  • 1Department of Lymphoma, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China.

Frontiers in oncology
|March 9, 2026
PubMed
概括

化学抗原受体T细胞 (CAR-T) 治疗对复发性/耐药性淋巴瘤显示出有前途. 然而,耐药性限制了它的有效性,需要对新目标和下一代CAR-T细胞进行研究.

关键词:
CAR (化学抗原受体) T细胞治疗2DLBCL - 扩散大的B细胞淋巴瘤.免疫逃避 免疫逃避分子向药物药物分子向药物电阻机制的电阻机制.瘤微环境 (TME) 是指瘤的微环境.

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