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Updated: Mar 10, 2026

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System
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All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System

Published on: December 20, 2021

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在胰腺癌中,m6A和YAP1机械传导通路之间的相互作用对于机械记忆和矩阵重塑至关重要

Jiaoshun Chen1,2, Gengqiao Wang1, Haoxiang Zhang3,4

  • 1Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

International journal of biological sciences
|March 9, 2026
PubMed
概括

胰腺癌细胞在硬的环境中获得机械记忆,由METTL14-YAP1反循环驱动. 这种循环促进了瘤的进展,并提出了新的治疗点.

关键词:
在CD166-EGFR-LOXL2轴上在METTL14中,使用的是METTL14一个YAP1一个YAP1矩阵的刚度 矩阵的刚度机械记忆 机械记忆是一种机械记忆.胰腺癌是一种癌症.

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