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Updated: Mar 10, 2026

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DNA聚合酶玛乙化 控制线粒体平衡和血管细胞衰老

Pengbo Wang1,2, Liming Yu3, Kexin Cao1

  • 1Department of Cardiology, First Hospital of China Medical University, Shenyang City, P. R. China.

International journal of biological sciences
|March 9, 2026
PubMed
概括

在Lys 1039的DNA聚合酶玛 (Polγ) 乙化调节血管衰老. 超乙化损害了线粒体DNA结合,降低了细胞收缩性,加速衰老,揭示了衰老中的新表观遗传代谢途径.

关键词:
乙化 乙化是一种DNA聚合酶 玛酶 是一种DNA聚合酶.人类大动脉光滑肌细胞线粒体的恒常状态是线粒体的恒常状态衰老是一种老化.

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