在儿科中与阳性细菌血液培养相关的特征
Pratik A Patel1,2, Lydia Lu3, Miguel A Locsin4
1Pediatric Infectious Disease, Children's Healthcare of Atlanta, Emory University Department of Pediatrics, Atlanta, GA.
Journal of the Pediatric Infectious Diseases Society
|March 9, 2026
概括
年龄,发烧和低血压等临床因素有助于识别儿童的细菌血流感染 (BSI). 大多数BSI在36小时内被检测出来,这有助于抗生素管理.
科学领域:
- 儿童传染病 儿童传染病
- 临床微生物学 临床微生物学
- 抗生素管理局 抗生素管理局
背景情况:
- 经验性抗生素的使用是常见的,等待细菌血流感染 (BSI) 结果.
- 识别BSI预测因子和培养时间到阳性 (TTP) 可以优化诊断和抗生素使用.
研究的目的:
- 分析与真正的BSI相关的临床特征与污染物.
- 确定影响BSI正值时间 (TTP) 的因素.
主要方法:
- 在儿科医疗保健系统中对阳性细菌血液培养的回顾性审查 (2021年3月至2022年6月).
- 根据临床管理,将培养物分类为BSI或污染物.
- 人口统计,临床数据和文化分析 TTP.
主要成果:
- 在1068种阳性培养中,71%被视为BSI.
- 脊髓炎与年龄小于90天,发烧/低温,低血压,中枢线或中性质衰竭有关.
- 长时间的TTP (>24小时) 与外围抽取,单个阳性培养和没有发烧有关.
结论:
- 儿科BSI的确定的临床特征.
- 大多数BSI在36小时内被确定.
- 数据可以为BSI评估提供血液培养采集指南.
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