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剪切波弹性图用于诊断乳腺病变在临床常规中的特征

Sylvia Kelemen¹, Tician Schnitzler², Simin Laures²

¹Faculty of Medicine, University of Basel, Basel, Switzerland.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

|March 9, 2026

概括

剪波弹性图 (SWE) 准确地区分恶性与良性乳腺病变,使用硬度测量. 这种定量超声波技术显示出高精度和特异性,可能减少乳腺癌诊断中不必要的活检.

科学领域:

医疗成像医学成像
在瘤学瘤学.
生物物理学的生物物理.

背景情况:

乳腺癌诊断面临的挑战是使用常规超声波将良性病变与恶性病变区分开来,导致不必要的活检.
通过剪波弹性学 (SWE) 进行定量组织刚度评估,有可能提高诊断准确性.

研究的目的:

评估SWE在乳腺病变的临床实践中的诊断准确性.
确定最佳的硬度切线值,以区分良性与恶性乳腺病变.

主要方法:

对73名BI-RADS 3-5病变的女性进行前性研究,在活检前接受SWE.
获得的刚度测量 (kPa,m/s);基因病理作为参考标准.
用于诊断性能和值确定的接收器操作特征 (ROC) 分析;评估可重现性.

主要成果:

恶性病变比良性病变 (平均18.7 kPa) 显著更硬 (平均56.7 kPa).
SWE实现了优异的诊断准确性 (AUC 0.932),最佳切断值为 40.03 kPa (3.6 m/s),产生 88% 的灵敏度和 95% 的特异性.
在硬度测量中观察到高的观察者内部和观察者间可重现性.

结论:

SWE是区分良性和恶性乳腺病变的准确方法,增强了特异性.
这种技术可能会减少不必要的乳腺活检率.
为了更广泛的临床实施,建议对SWE协议进行标准化.

关键词:

在 BI-RADS 会议上.乳腺癌乳腺癌乳腺癌诊断的准确性诊断的准确性剪波弹性图形剪波弹性图形超声波超声波是指超声波的使用.

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