跨直肠与跨膜前列腺活检:一个系统的审查和元分析
Gavin G Calpin1,2, Cian M Hehir2, Mariyah Alzayer2
1Department of Urology, St. Vincent's University Hospital, Dublin, Ireland.
BJU international
|March 9, 2026
概括
在局部麻醉下进行的穿膜 (LATP) 活检显示,感染和败血症的发生率低于穿膜超声波 (TRUS) 活检. LATP活检还可以改善前列腺癌的检测,包括临床上显著的癌症.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 跨直肠超声波 (TRUS) 活检是诊断前列腺癌的常见方法.
- 跨关节活检技术在降低感染风险方面具有潜在的优势.
研究的目的:
- 为了比较局部麻醉性跨关节 (LATP) 活检与TRUS活检的疗效和安全性.
- 评估两种活检方法的癌症检测率和并发症概况.
主要方法:
- 随机对照试验和前性研究的系统审查和元分析.
- 包括12项与8497名患者进行的研究,比较LATP和TRUS活检.
主要成果:
- 在LATP活检中,感染率 (RR 0.68) 和败血症 (RR 0.16) 率显著降低.
- 总体癌症检测 (RR 1.07) 和临床显著的癌症 (格莱森等级组2-5) 检测 (RR 1.12) 在LATP活检时更高.
- 在LATP和TRUS活检组中,尿留率与LATP和TRUS活检组相似.
结论:
- LATP活检是一种比TRUS活检更安全的替代方案,减少了感染和败血症的发生率.
- LATP活检提供了更优质的前列腺癌检测,特别是临床上显著的形式.
- 这些发现支持LATP活检作为前列腺癌诊断的首选方法.
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