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相关概念视频

Kinematic Equations - I01:26

Kinematic Equations - I

13.2K
When an object moves with constant acceleration, the velocity of the object changes at a constant rate throughout the motion. The kinematic equations of motions are derived for such cases where the acceleration of the object is constant. The first kinematic equation gives an insight into the relationship between velocity, acceleration, and time. We can see, for example:
13.2K
Kinematic Equations - II01:17

Kinematic Equations - II

12.1K
The second kinematic equation expresses the final position of an object in terms of its initial position, the distance traveled with the initial constant velocity, and the distance traveled due to a change in velocity. Similar to the first kinematic equation, this equation is also only valid when the acceleration is constant throughout the motion of an object.
Suppose a car merges into freeway traffic on a 200 m long ramp. If its initial velocity is 10 m/s and it accelerates at 2 m/s2, then the...
12.1K
Kinematic Equations - III01:18

Kinematic Equations - III

9.9K
The first two kinematic equations have time as a variable, but the third kinematic equation is independent of time. This equation expresses final velocity as a function of the acceleration and distance over which it acts. The fourth kinematic equation does not have an acceleration term and provides the final position of the object at time t in terms of the initial and final velocities. This equation is useful when the value of the constant acceleration is unknown.
Using the kinematic equations,...
9.9K
Conservation of Angular Momentum: Application01:18

Conservation of Angular Momentum: Application

8.7K
A system's total angular momentum remains constant if the net external torque acting on the system is zero. Examples of such systems include a freely spinning bicycle tire that slows over time due to torque arising from friction, or the slowing of Earth's rotation over millions of years due to frictional forces exerted on tidal deformations. However in the absence of a net external torque, the angular momentum remains conserved. The conservation of angular momentum principle requires a...
8.7K
Equation of Rotational Dynamics01:08

Equation of Rotational Dynamics

11.8K
Angular variables are introduced in rotational dynamics. Comparing the definitions of angular variables with the definitions of linear kinematic variables, it is seen that there is a mapping of the linear variables to the rotational ones. Linear displacement, velocity, and acceleration have their equivalents in rotational motion, which are angular displacement, angular velocity, and angular acceleration. Similar to the rotational variables, a mapping exists from Newton's second law of motion...
11.8K
Kinematic Equations for Rotation01:30

Kinematic Equations for Rotation

1.1K
In mechanics, when one observes a rigid body in rotational motion with constant angular acceleration, it is possible to establish equations for its rotational kinematics. This process resembles how linear kinematics are dealt with in simpler motion studies.
For instance, imagine a point A on a rigid body engaged in circular motion. The translational velocity of this particular point can be calculated by taking the time derivatives of the displacement equation, which essentially measures the...
1.1K

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相关实验视频

Updated: May 2, 2026

Proton Transfer and Protein Conformation Dynamics in Photosensitive Proteins by Time-resolved Step-scan Fourier-transform Infrared Spectroscopy
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Proton Transfer and Protein Conformation Dynamics in Photosensitive Proteins by Time-resolved Step-scan Fourier-transform Infrared Spectroscopy

Published on: June 27, 2014

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使用KEnRef抑制互质子角和距离动力学.

Amr Alhossary1, Colin A Smith1

  • 1Department of Chemistry, Wesleyan University, Middletown, Connecticut 06457, United States.

The journal of physical chemistry. B
|March 9, 2026
PubMed
概括
此摘要是机器生成的。

通过严格考虑质子间距离和角度波动,KEnRef精炼了蛋白质结构. 这种新的方法使得基于超定量核磁共振 (NMR) 的集合精细化,改善结构和动态属性建模.

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相关实验视频

Last Updated: May 2, 2026

Proton Transfer and Protein Conformation Dynamics in Photosensitive Proteins by Time-resolved Step-scan Fourier-transform Infrared Spectroscopy
10:03

Proton Transfer and Protein Conformation Dynamics in Photosensitive Proteins by Time-resolved Step-scan Fourier-transform Infrared Spectroscopy

Published on: June 27, 2014

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Quantifying Intermembrane Distances with Serial Image Dilations
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Quantifying Intermembrane Distances with Serial Image Dilations

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Study of Protein Dynamics via Neutron Spin Echo Spectroscopy
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科学领域:

  • 生物物理学的生物物理.
  • 计算生物学 计算生物学
  • 结构生物学 结构生物学

背景情况:

  • 传统的NMR结构确定受复杂的数学限制,忽视了质子间角运动.
  • 由于忽视了动态效应,精确的NOE (eNOE) 和残极二极合 (RDC) 等先进的方法缺乏物理现实性.

研究的目的:

  • 介绍KEnRef,一个开源的C++库,用于改进多态蛋白质结构.
  • 严格考虑结构细化中的质子间距离和角度波动.
  • 为了实现基于NMR的超定量组合精细化.

主要方法:

  • 在KEnRef.中实施了动态合奏方法.
  • 开发了一种新的损失函数,用于平衡灵敏度的分数指数.
  • 集成KenRef与GROMACS进行分子动力学模拟.

主要成果:

  • 在单结构模拟中实现了~0.2 Å 间质子RMSD和2 ns的合时间.
  • 在双结构组合中,已经证明了100倍的约束能降低和高度相关的距离/角度波动 (R > 0.85).
  • 验证了KEnRef捕获局部蛋白质运动和动态特性的能力.

结论:

  • KEnRef使距离和角度波动的综合精细化能够进行准确的结构和动态建模.
  • 图书馆的性能和模块化设计支持基于NMR的高级组合精细化.
  • KEnRef提供了使用NMR数据对蛋白质动态的超定量分析的基础.