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从零售肉中分离的多抗药性肠病原菌大肠杆菌的分子查和抗生素样本

Sakibul Haque Zilon¹, Hemayet Hossain², Md Shahidur Rahman Chowdhury³

¹Department of Pathology, Sylhet Agricultural University, Sylhet, Bangladesh.

Veterinary medicine and science

|March 9, 2026

概括

在孟加拉国,在肉中发现了耐多药性肠道病原菌大肠杆菌 (MDR-EPEC). 这凸显了改善食品安全和抗生素使用的必要性,以保护公共健康.

科学领域:

食品微生物学食品微生物学
公共卫生公共卫生
抗微生物耐药性抗微生物耐药性

背景情况:

零售肉中的肠病原性大肠杆菌 (EPEC) 构成重大公共卫生风险,特别是在脆弱人群中.
受污染的肉是EPEC传播的潜在载体.

研究的目的:

确定肉中多药耐药EPEC (MDR-EPEC) 的流行率,遗传特征和耐药性模式.
评估MDR-EPEC在研究区域的公共卫生影响.

主要方法:

从孟加拉国库利尔查尔和巴伊拉布收集了140个零售肉样本.
使用初级培养,生物化学测试和PCR (phoA,eaeA基因) 确认了EPEC分离物.
通过磁盘扩散进行了抗微生物敏感性测试,并分析了基因型模式.

主要成果:

大肠杆菌的流行率为68.6%,EPEC在8.6%的隔离物中被发现.
所有EPEC菌株对安培素有耐药性;对塞夫塔齐迪姆和 جنت米辛观察到高耐药性.
所有12个EPEC分离物被归类为MDR,显示对多种抗生素类别的耐药性.
基因分析显示,像blaTEM-1,2和aac(3)-iv这样的耐药基因的高患病率表明了广泛的耐药性.

结论:

调查结果强调迫切需要加强食品安全法规和控制措施.
促进合理的抗生素使用和改善卫生实践,以减轻MDR-EPEC传播.
强调在肉中解决MDR-EPEC对于保护公共健康的重要性.

关键词:

埃舍里希亚大肠杆菌 (Escherichia coli) 是一个大肠杆菌.在 MDR-EPEC 中.抗微生物耐药性抗微生物耐药性肉肉类肉肉类食物传播的病原体

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