概括
这一案例突显了一个罕见的儿童骨关节结核病病例.
科学领域:
- 儿童传染病 儿童传染病
- 整形外科手术 整形外科手术
- 菌株学 菌株学 菌株学
背景情况:
- 肺外结核不常见,骨关节干扰,特别是在脚,在儿童中特别罕见.
- 一个以前健康的10.5岁的男性在轻微创伤后出现了2个月的左脚胀,疼痛和有限的运动能力.
研究的目的:
- 报告一个罕见的儿科骨关节结核病的脚.
- 强调在患有异常脚表现的儿科患者中考虑结核病的重要性.
主要方法:
- 诊断工作包括血液测试 (CBC,CRP,ESR),培养,结核病T细胞点检测 (T-SPOT.TB),超声导向吸收和手术脱bridement.
- 样品经过细菌培养,酸快细菌检测,病理活检和Mycobacterium结核病的测序与里法皮辛耐药性分析.
主要成果:
- 病理学发现了慢性结核性颗粒状炎症.
- 基因测序检测到M. 结核综合体没有抗利芬素;T-SPOT.TB测试呈阳性.
- 患者接受了经验性抗生素治疗,随后进行了特定的抗结核治疗 (伊索尼亚齐德,利芬素,皮拉津胺,乙墨托尔).
结论:
- 足的儿科骨关节结核病是罕见的,但应考虑在持续,不明原因的足炎症和疼痛的情况下.
- 早期诊断和适当的抗结核治疗对于儿童的良好结果至关重要.
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