老年营养风险指数和肺功能预测了食道切除术后的非食道癌相关死亡率
Shinsuke Sato1, Eiji Nakatani2, Philip Hawke3
1Department of Gastroenterological Surgery, Shizuoka General Hospital, 4-27-1 Kitaando, Aoi-ku, Shizuoka, 420-8527, Japan. shinsukesato@gmail.com.
概括
在手术后确定非食道癌死亡的危险因素至关重要. 较低的营养状况 (老年营养风险指数) 和肺功能 (百分比生命能力) 预测食道癌患者的死亡率.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 老年医学 老年医学
背景情况:
- 手术后食道癌的预后因素得到了充分研究.
- 非食道癌相关死亡的危险因素尚不清楚.
- 这项研究旨在确定食道切除术后非食道癌死亡率的预测因素.
研究的目的:
- 鉴定食道切除术后非食道癌相关死亡的预测因素.
- 了解治愈性食道癌手术后的长期死亡趋势.
- 为脆弱患者提供术后管理策略的信息.
主要方法:
- 对398名因食道或食道胃结癌而接受食道切除术的患者进行了回顾性分析.
- 排除非治愈切除,特殊组织学或在医院死亡的患者.
- 因果特异性考克斯回归和累积发病率函数 (CIF) 分析与竞争风险.
主要成果:
- 非食道癌死亡人数 (n=63) 归因于呼吸系统疾病,第二种癌症和其他原因.
- 患有非食道癌死亡的患者年龄较大,老年营养风险指数 (GNRI) 和体重指数较低,高血压率较高.
- 非食道癌相关死亡的独立预测因素包括年龄,百分比生命能力 (%VC) 和GNRI.
结论:
- 低GNRI和%VC是治疗性食道切除术患者非食道癌相关死亡的独立预测指标.
- 营养和肺部状况的术前评估对于识别高风险患者至关重要.
- 这种评估可以指导量身定制的术后管理和支持性护理,以改善结果.
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