从系统性审查中识别的实施前研究中解读和报告实施策略和试验设计领域的实用属性的框架:一个方法论研究:从系统性审查中识别的试验设计领域的实用属性
Rahma Ajja1, Vidhya Suresh2, Sean Wang1
1Wake Forest University School of Medicine, Winston Salem, North Carolina, USA.
本研究提出了一本实用手册,用于报告高血压管理远程医疗中的实施策略 (IS) 和试验设计. 它有助于研究人员评估基于证据的干预措施,以便在现实世界中做好准备.
科学领域:
- 实施科学 实施科学
- 医疗保健服务研究 医疗服务研究
- 数字健康数字健康
背景情况:
- 远程医疗在改善高血压管理方面表现有前途,但在日常护理中面临着有限的采用.
- 实施策略 (IS) 对于加强基于证据的干预措施 (EBI) 的使用至关重要.
- 从预实施研究中系统报告IS和试验设计对临床研究人员来说是个挑战.
研究的目的:
- 开发和描述用于高血压管理的远程医疗试验中用于报告IS的系统方法.
- 用PRECIS-2工具评估这些试验的实用性,使用PRagmatic解释连续性指标摘要-2 (PRECIS-2).
- 帮助临床研究人员评估EBI的现实世界准备.
主要方法:
- 一项系统性审查确定了13项用于高血压管理的远程医学试验.
- 使用实用实施战略报告工具 (PISRT) 以后期报告IS.
- 实用解释连续性指标摘要-2 (PRECIS-2) 工具评估了试验设计领域.
- 三名接受实施科学培训的临床研究人员在专家咨询下进行了数据提取和分析.
主要成果:
- 开发了一本实用手册,用于系统报告IS和试验设计属性.
- 这种方法有助于评估远程医疗干预措施的高血压管理在有效性-有效性谱的评估.
- 详细阐述了IS在高血压远程医疗中的实施示例.
结论:
- 提供了一份逐步的手册,以支持临床研究人员报告IS并评估EBI准备好用于现实世界的应用.
- 描述的方法旨在加快EBI转化为常规护理.
- 建议进一步评估这些报告方法的有效性.
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