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布普伦诺芬悖论:布普伦诺芬如何触发和解决阿片类药物戒断问题

Mehdi Haghdoost1, Jennifer LaBranche2,3, Matthew Roberts1,2

  • 1Aidos Innovation, Sheridan, Wyoming, USA.

Addiction biology
|March 9, 2026
PubMed
概括

治疗阿片类药物使用障碍 (OUD) 的布普伦诺芬 (BUP) 可能会导致由于其高片受体 (MOR) 亲和力而导致急性戒断. 新的见解表明,MOR外部化和NOP受体活性解释了这一效应,有助于优化OUD治疗.

关键词:
有偏见的激进主义者.布普伦诺啡因是一种-阿片类受体受体的受体"阿片类药物使用障碍"快速提取方式 (precipitated withdrawal) 是一种提取方式.

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