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Updated: Mar 11, 2026

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis

Published on: March 19, 2019

[在治疗坎迪达菌感染方面的创新]

Susanne Fadlalla¹, Rosanne Sprute¹, Oliver A Cornely¹

¹Klinik I für Innere Medizin, Universitätsklinikum Köln, Köln, Deutschland.

Deutsche medizinische Wochenschrift (1946)

|March 9, 2026

概括

耐药性Candida感染是一个日益增长的全球威胁. 新的指导方针和抗真菌疗法为侵袭性 кандидоз提供了改进的诊断和管理策略.

科学领域:

医学真菌学医学真菌学
传染性疾病传染性疾病
抗微生物耐药性抗微生物耐药性

背景情况:

全球范围内Candida感染的发病率不断上升.
药物耐药的Candida分离物的患病率增加,包括Candida auris和Candida parapsilosis.
在Candida glabrata中,阿佐尔和赤素耐药性所带来的挑战.

研究的目的:

总结了欧洲医学真菌学联合会 (ECMM) 2025年5月关于坎迪达菌感染的全球指南中的关键更新.
突出新的诊断和管理建议.
讨论针对侵袭性 кандидоз的新兴治疗方案.

主要方法:

审查最新的欧洲医学真菌学联合会 (ECMM) 全球指南.
分析欧洲抗菌感应性测试委员会 (EUCAST) 更新的Candida auris.
包括关于新批准和正在研究的抗真菌剂的信息.

主要成果:

该指南纳入了修订后的分类学,并强调非白虫的Candida物种.
现在可以获得Candida auris的新EUCAST断点.
雷扎芬金,伊布雷克萨芬格尔普和福斯曼格皮克斯代表了扩展的治疗选择.

结论:

更新后的ECMM指导方针在管理Candida感染方面取得了关键进展.
新的抗真菌剂和断点增强了对耐药菌株的治疗策略.
这些进展对于保护免疫功能受损和重症患者至关重要.

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