暴露前预防在英国的献血者中使用
Jaid Debrah1, Claire Reynolds2, Victoria Maddox3
1Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Vox sanguinis
|March 9, 2026
概括
许多同性恋,双性恋和其他与男性发生性关系的男性 (GBMSM) 继续使用暴露前预防 (PrEP) 尽管被诊断为梅毒,这表明潜在的献血指南未遵守. 这凸显了需要改善捐助者教育和有针对性的公共卫生干预措施的需要.
科学领域:
- 血液安全研究 血液安全研究
- 公共卫生干预措施 公共卫生干预
- 性健康流行病学性健康流行病学
背景情况:
- 针对个体化风险评估 (FAIR) 的框架旨在减少在选择献血者时的耻辱感.
- 暴露前预防 (PrEP) 使用将个人排除在献血之外,影响同性恋,双性恋和其他与男性发生性关系的男性 (GBMSM).
研究的目的:
- 为了检查英格兰梅毒的男性献血者之间的暴露前预防 (PrEP) 使用情况.
- 评估遵守献血指导方针,并评估对血液安全的影响.
主要方法:
- 来自梅毒阳性男性献血者 (2018-2024) 的残留血样本进行了PrEP检测.
- 分析了人口统计数据和报告的PrEP使用情况.
主要成果:
- 梅毒阳性捐赠从2018年到2024年大幅增加.
- 梅毒病例的比例上升被归因于GBMSM.
- 7.1%的梅毒阳性男性献血者在2023年对PrEP的检测结果呈阳性,表明不符合规定.
结论:
- 持续使用PrEP表明,有关献血资格的捐赠者教育存在差距.
- 需要有针对性的公共卫生干预措施来改善性健康教育和对捐赠标准的认识.
- 进一步研究与高风险性行为相关的其他感染是有必要的.
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