在背部大脑网络内功能连接的早期成熟
Kristina T R Ciesielski1,2, Sheraz Khan1, Koene R Van Dijk1
1Department of Radiology, MGH/MIT Athinoula A. Martinos Center for Biomedical Imaging, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.
Brain connectivity
|March 9, 2026
概括
这项研究表明,后背脑网络在儿童中成熟得很早,而腹视觉网络则表现出发育延迟. 阿尔法带连接差异突出了视觉神经科学中的这些独特的发展轨迹.
科学领域:
- 神经科学是一个神经科学.
- 发育神经科学的发展神经科学.
- 认知神经科学 认知神经科学
背景情况:
- 已建立的视觉神经科学研究详细介绍了背部 (DVN) 和腹部 (VVN) 视觉网络.
- 这些网络中的功能连接的发展轨迹仍未得到充分研究.
研究的目的:
- 调查DVN和VVN内部功能网络连接的年龄相关差异.
- 检查阿尔法频段振荡的发育过程作为认知抑制控制的标记.
主要方法:
- 休息状态磁脑电图 (rsMEG) 用于比较年轻 (6-12岁) 和年长 (18-29岁) 的男性参与者的功能连接.
- 阶段滞后指数和图形理论指标被用来分析网络内部和网络之间的连接.
- 用先前的rsfMRI和MRI形态测量数据来定义皮层网络节点.
主要成果:
- 阿尔法频段功率光谱密度在各年龄组之间是可比的,表明信号质量相似.
- 年轻的参与者在后背部区域 (DVN,DMN) 显示出更高的网络内连接性,但对VVN的前部连接性减少.
- 在前背/中皮层观察到阿尔法连接的显著差异,年轻个体的连接性较低.
结论:
- 这些发现支持后背脑网络的早期成熟,与之前的人类和灵长类神经成像研究一致.
- 年轻参与者的前部VVN连接减少表明这个网络的发展时间表延长了.
- 阿尔法频段振荡连接是视觉网络成熟时发育变化的有价值指标.
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