101个夜班和日班工人在工业中的心血管风险因素. 一个横截面研究
Marit Skogstad1, Sarah Alsaedi1, Per Anton Sirnes2
1National Institute of Occupational Health (STAMI), Box 5330 Majorstuen, 0304 Oslo, Norway.
Journal of occupational and environmental medicine
|March 10, 2026
概括
轮班夜班工作增加了心血管疾病 (CVD) 风险因素,如炎症. 减少夜班和增加恢复时间可能有助于减轻轮班工人的这些风险.
科学领域:
- 职业健康 职业健康 职业健康
- 心血管医学 心血管医学
- 内分泌学 在内分泌学.
背景情况:
- 轮班夜班工作在工业环境中很普遍.
- 以前的研究表明,轮班工作与不良健康结果之间存在潜在的联系,包括心血管疾病 (CVD).
- 了解与不同夜班负载相关的特定心血管疾病风险因素对于预防策略至关重要.
研究的目的:
- 评估和比较工业轮班夜班工人与日班工人的心血管疾病 (CVD) 风险因素.
- 调查夜班工作量,睡眠时间和心血管疾病风险标志物之间的关联.
- 为了识别受夜班工作影响的特定炎症标志物和基因.
主要方法:
- 横截面研究设计,涉及27名白天工人和74名夜班工人 (按高和低夜班负载分类).
- 评估睡眠模式,血压 (BP),脉冲波速率 (PWV),心动脉内膜介质厚度 (cIMT),最大氧气吸收 (V̇O2max).
- 生物化学分析包括糖基化血红蛋白 (HbA1c),脂质,炎症标记物和阿迪波金 (例如,阿迪波涅丁).
主要成果:
- 与白天工作者和较低负荷夜班工作者相比,高负荷夜班工作者表现出炎症升高和脂蛋白水平降低.
- 8小时和12小时的夜班都与睡眠时间的减少有关.
- 增加的夜班数量与炎症标志物有积极的相关性,与阿迪波内克水平有负相关性.
结论:
- 轮班夜班工作与心血管疾病 (CVD) 风险因素的增加有显著联系.
- 减小夜班数量并允许延长恢复时间的轮班工作时间表可能有助于减轻这些风险.
- 进一步研究优化轮班安排是有必要的,以保护轮班工人的心血管健康.
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