身体活动与尿道癌症风险的关联:系统性审查和元分析
Fangfang Xie1, Chaoqu Xie1, Hongyu Yue1
1School of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Nature communications
|March 10, 2026
概括
高度体力活动 (PA) 显著降低了泌尿系统癌症 (UC) 的风险,包括膀,前列腺和类型. 这一发现支持PA作为预防癌症和改善健康结果的关键策略.
科学领域:
- 在瘤学瘤学.
- 预防医学 预防医学
- 流行病学 流行病学
背景情况:
- 泌尿器癌 (UC) 是一个重大的全球健康挑战.
- 身体活动 (PA) 在减轻UC风险中的作用尚未完全理解.
- 现有的研究往往侧重于个别的UC站点,而不是集体风险.
研究的目的:
- 综合评估身体活动 (PA) 与尿道癌症 (UC) 的整体风险之间的关联.
- 量化特定UC类型的风险降低,包括膀,前列腺和癌,与PA水平相关.
主要方法:
- 95项研究的元分析,包括176个风险估计.
- 包括来自11,255,721名参与者的数据.
- 基于研究设计 (病例控制与队列) 和参与者人口统计 (性别) 的分层分析.
主要成果:
- 高水平的PA与9%的整体UC风险降低有关.
- 观察到的特定风险降低:膀癌13%,前列腺癌6%,癌11%.
- 在病例控制研究中发现的更强烈的关联,在妇女中,和职业PA相比娱乐PA.
结论:
- 身体活动 (PA) 与尿道癌 (UC) 风险有显著的反向关系.
- 作为潜在的预康复,可以提高身体健康和降低UC发病率.
- 国际指导方针应促进PA用于UC风险降低,而进一步的研究应确定最佳PA参数.
相关概念视频
Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
Disorders of the Male Reproductive System
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Nursing Assessment of the Genitourinary System I: Health History
The genitourinary system is critical to maintaining fluid balance, waste elimination, and reproductive function. Nurses play a vital role in assessing this system, beginning with a thorough health history. This process involves gathering patient information, identifying risk factors, and recognizing symptoms of genitourinary disorders. Early detection is vital for timely interventions and management.1. Gathering Patient InformationA complete health history includes the patient’s personal,...
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
Urinary Tract Calculi IV: Nutrition Therapy and Prevention
Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...


