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Updated: Mar 11, 2026

Phage-Mediated Genetic Manipulation of the Lyme Disease Spirochete Borrelia burgdorferi
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细菌的Schlafen蛋白调解菌体的防御作用

Veronica Perez Taboada1, Yimo Wu1, Riley Cassidy1

  • 1Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, USA.

Nature microbiology
|March 10, 2026
PubMed
概括

Prokaryotic Schlafen核酶是古代的抗病毒蛋白质,通过分裂转移RNA (tRNA) 来保护细菌免受菌体的侵害. 这一发现揭示了从细菌到人类保存的tRNA向免疫的深层进化起源.

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