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Updated: Mar 11, 2026

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
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Published on: July 11, 2025

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一个可编程的平台,使得有针对性的染色体替代和跨物种稳定性分析成为可能

Lei Shi1, Xiali Yang1, Mingdi Wu1

  • 1Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, State Key Laboratory of Genome and Multi-omics Technologies, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, 518120, China.

Protein & cell
|March 10, 2026
PubMed
概括

我们开发了一种使用CRISPR/Cas9和微细胞介导染色体转移 (MMCT) 来创建染色体置换菌株 (CSS) 的新方法. 这个平台 (TEAM) 允许精确的染色体替换,用于研究哺乳动物的复杂特征和基因组进化.

关键词:
这就是CRISPR/Cas9的作用.这是一个MMCTCT.染色体消除是染色体的消除.染色体替代菌株 染色体替代菌株

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