工作日晚睡时间与胆结石的患病率增加有关:一项基于人口的研究
Man Liu1, Yanqing Gong1,2, Yingxi Su1
1Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, NO. 154 Anshan Road, Tianjin, 300041, China.
European journal of medical research
|March 10, 2026
概括
延迟工作日睡觉时间增加了胆结石 (GS) 的患病率,特别是在40岁以上的人群中. 这项研究强调了晚睡时间表与更高的GS风险之间的联系.
科学领域:
- 流行病学 流行病学
- 睡眠医学 睡眠医学
- 胃肠病学 胃肠病学
背景情况:
- 睡眠模式和胆结石 (GS) 形成之间的联系尚未得到充分证实.
- 研究睡眠特征可能会揭示胆结石的新风险因素.
研究的目的:
- 检查各种睡眠特征与胆结石 (GS) 患病率之间的关联.
- 为了确定人口和生活方式因素是否会改变睡眠和GS之间的关系.
主要方法:
- 国家健康和营养检查调查 (2017-2020) 数据的横截面分析.
- 包括7329名参与者 (≥20岁) 的睡眠和GS问卷数据.
- 二元逻辑回归和分层分析以评估睡眠特征和GS患病率,调整混因素.
主要成果:
- 总共分析了7329名参与者,其中736人报告了GS病史.
- 延迟工作日睡觉时间与增加GS的几率相关 (OR=1.09每小时延迟).
- 与18:00-20:00相比,晚些时候的睡觉时间 (22:00-06:00) 观察到显著更高的GS概率.
- 年龄是一个显著的效果修饰因素;40岁以上的个体显示,延迟睡觉时间和GS (OR=1.14) 之间存在更强的关联.
- 没有发现醒来时间,睡眠时间或睡眠障碍与GS患病率之间有显著的关联.
结论:
- 延迟工作日入睡时间是胆结石 (GS) 患病率的重要风险因素.
- 睡前和GS之间的关联因年龄而变化,老年人 (>40岁) 更容易受到影响.
- 睡眠时间,特别是工作日晚些时候的睡觉时间,应该在胆结石预防策略中考虑.
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