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Updated: Mar 11, 2026

Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis
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人类IDO2表现出与人类IDO1不同的独特结合亲和力

Shunsuke Nogi1, Ayumu Takahashi1, So Murakami1

  • 1Graduate School of Pharmaceutical Sciences, The University of Osaka, Suita, Japan.

The FEBS journal
|March 10, 2026
PubMed
概括

印度醇胺2,3-二氧化酶2 (IDO2) 具有较低的催化活性,这是由于其独特的L-托结合. 替换一个关键残留物 (His143) 显著增强IDO2活性,揭示了对酶功能的洞察力.

关键词:
晶体结构 晶体结构黑姆蛋白质是什么 黑姆蛋白质是什么类胺2,3-二氧化基酶的存在结合的结合位置.通过光谱学方法.

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