纵向远程6分钟步行距离和心脏努力使用可穿戴传感器在肺高血压
Daniel Lachant1, Nishit Agarwal2, Kyle Norton1
1Division of Pulmonary and Critical Care University of Rochester Medical Center Rochester New York USA.
Pulmonary circulation
|March 10, 2026
概括
使用可穿戴传感器进行远程家庭6分钟步行测试 (6MWT) 对肺高血压 (PH) 患者来说是安全可靠的. 这种方法准确地跟踪了随着时间的推移而发生的功能变化,反映了临床结果并改善了患者监测.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 生物医学工程 生物医学工程
背景情况:
- 在肺高血压 (PH) 中,远程6分钟步行测试 (6MWT) 显示了安全性,但缺乏关于纵向耐久性和与临床测试的相关性数据.
- 心脏努力 (CE) 提供了超越仅仅步行距离的生理背景.
研究的目的:
- 用可穿戴传感器评估家用6MWT和CE的纵向性能和耐用性.
- 在PH患者的8周时间内,将远程家庭测试与监督的临床测试进行比较.
主要方法:
- 一项前性,单中心研究,涉及29名PH参与者.
- 参与者在基线和第8周接受了监督的临床和无监督的家庭6MWT.
- 一个可穿戴的胸部传感器记录了心率和加速以估计距离和计算CE,并使用混合效应模型和Bland-Altman分析进行分析.
主要成果:
- 传感器估计的6MWT距离和CE显示出最小的偏差和与临床测量 (ICC > 0.995) 的良好一致.
- 基于家庭的6MWD比基于诊所的测试低约40米,但在家庭和诊所之间纵向变化有显著的相关性 (6MWD r=0.40,CE r=0.42).
- 在远程测试期间没有报告任何不良事件.
结论:
- 使用可穿戴传感器的家用6MWT和CE是安全的,可行的和可靠的,用于PH的远程功能评估.
- 这种方法证明了与临床测试相比的纵向跟踪,可能可以更早地检测临床变化并改善治疗管理.
- 频繁的远程监测可以扩大PH患者获得标准化生理评估的机会.
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