在前性发作中的直肠半学:一个系统的审查
Erika Ignatius1, Liisa Metsähonkala1, Henna Jonsson1
1Department of Child Neurology, Epilepsia Helsinki, a Full Member of ERN EpiCARE, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
概括
从前发作的发作往往伴有前体,视觉或身体感知错觉. 需要进一步的研究才能充分理解这些后皮层发作.
科学领域:
- 神经学 神经学
- 发病学 (Epileptology) 是一个专业的学科.
- 神经科学是一个神经科学.
背景情况:
- 后部默认模式网络中的一个关键枢纽Precuneus,越来越多地被认为是潜在的发作焦点.
- 了解前性发作的直肠半学,对于准确的诊断和手术前评估至关重要.
研究的目的:
- 系统地回顾和描述从前发作中产生的发作的ictal semiology.
- 为在手术前评估的背景下解释发作提供指导.
主要方法:
- 系统性审查遵循系统性审查和元分析 (PRISMA) 和诊断准确性研究 (QUADAS2) 准则的质量评估工具的首选报告项目.
- 在PubMed和Embase的搜索中,使用关键词进行了与前,头/后,视频脑电图 (视频EEG) 和手术相关的搜索.
- 数据提取和选由两名独立审查员进行,证据质量使用推评估,开发和评估 (GRADE) 方法进行评级.
主要成果:
- 分析了9项研究,其中包括29名患有前性发作的患者.
- 常见的初始症状包括前庭干扰,视觉错觉/幻觉和改变身体感知.
- 运动症状通常发生晚些时候,表明发作传播.
- 证据的整体质量被评为中等到低.
结论:
- 这一综述表明,特征性发作症状与前性发作相关,例如感觉和感知障碍.
- 报告的病例显著稀少,凸显出需要进行更广泛的研究.
- 具有详细的解剖电临床数据的大型前性研究对于全面了解后皮层的频谱内的前性发作至关重要.
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