Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

812
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
812
Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

59
Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
59

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Multifocal Skeletal Muscle Mineralisation Following Severe Trauma and Prolonged Critical Illness: A Case Report.

Cureus·2026
Same author

LC-MS-Based Metabolomics and Proteomics Sample Preparation of Urine: Methods and Multi-Omics Integration.

Advances in experimental medicine and biology·2026
Same author

Evaluation of FASP for Mass Spectrometry-Based Untargeted Metabolomics Analysis of Urine Samples.

Journal of proteome research·2026
Same author

Current understanding and future directions in severe asthma through artificial intelligence-integrated multi-omic approaches.

European respiratory review : an official journal of the European Respiratory Society·2026
Same author

Proteomic and metabolomic profiling of methicillin-resistant <i>Staphylococcus aureus</i> associated with invasive vs. non-invasive infections: uncovering key biomarkers and pathogenic pathways.

Frontiers in microbiology·2026
Same author

Long-Term Cardiovascular Outcomes Following New-Onset Arrhythmias During Pregnancy.

Pacing and clinical electrophysiology : PACE·2026

相关实验视频

Updated: Mar 12, 2026

Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings
10:26

Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings

Published on: August 18, 2023

6.6K

在中东的泛基倡议.

Bassam Jamalalail1, Mohammad Amiruddin Hashmi1, Mohamed A Almarri2,3

  • 11Center for Applied and Translational Genomics, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, United Arab Emirates; email: alawi.alsheikhali@dubaihealth.ae, mohammed.uddin@dubaihealth.ae.

Annual review of genomics and human genetics
|March 10, 2026
PubMed
概括

潘格诺姆计划超越了单一的人类参考,以捕捉全球的多样性. 中东的泛基因组项目正在揭示独特的遗传变异,这些变异对于精准医学至关重要.

更多相关视频

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit
22:10

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit

Published on: June 28, 2013

13.8K
Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
06:18

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

15.0K

相关实验视频

Last Updated: Mar 12, 2026

Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings
10:26

Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings

Published on: August 18, 2023

6.6K
Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit
22:10

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit

Published on: June 28, 2013

13.8K
Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
06:18

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

15.0K

科学领域:

  • 基因组学就是基因组学.
  • 生物信息学是一种生物信息学.
  • 人口遗传学 人口遗传学

背景情况:

  • 人类基因组参考 (GRCh38) 是全球遗传多样性的一个例子.
  • 以前的基因组资源在很大程度上排除了代表性不足的人群,特别是来自中东的人群.
  • 测序和生物信息学的进步正在使更全面的基因组分析成为可能.

研究的目的:

  • 审查核心的庞然大物概念和当前的举措.
  • 为了调查中东国家的庞然大物努力.
  • 突出该地区的基因架构和对精准医学的影响.

主要方法:

  • 综述万科动物概念和现有文献.
  • 中东国家基因组计划和泛基因组计划的调查.
  • 对二倍体组件的长读测序和基于图形的生物信息学的分析.
  • 检查人口特异性遗传因素 (创始人效应,血缘关系,内婚关系).

主要成果:

  • 泛基因组计划正在将重点转移到双体组合和种群单体类型.
  • 中东的基因组研究正在识别出新的序列和变异内容,这些内容不在当前的参考文献中.
  • 创始人效应,血缘关系和内婚关系显著塑造了该地区的遗传架构,影响了同卵性和罕见等位基因的运行.
  • 六个国家的现有国家基因组计划正在开始纳入泛基因组战略.

结论:

  • 协调,区域范围的泛基因组计划对于公平的基因组参考是必不可少的.
  • 改进的映射和对中东单元类型的变异调用将增强临床解释.
  • 加快精准医学需要来自不同人群的全面基因组数据.