大体费里丁重链-同核素调节轴在损伤期间调节铁亡

Tanima Chatterjee1, Sarah Machado1, Kellen Cowen1

  • 1Division of Nephrology, The University of Alabama at Birmingham, Birmingham, United States of America.

JCI insight
|March 10, 2026
PubMed
概括

在巨细胞中肌状铁素重链 (FtH) 缺乏会在急性损伤 (AKI) 期间促进铁亡. 这涉及到α-synuclein (SNCA) 诱导,加剧铁体平衡和损伤.