过量预防网站关闭后的医疗保健利用率和死亡率:使用细分差异时间序列的相关队列分析
Nathaniel Day1,2, Kym Kaufmann1, Daniel John Alexander Devoe1
1Canadian Centre of Recovery Excellence (CoRE), Calgary, Canada.
Addiction (Abingdon, England)
|March 10, 2026
概括
红鹿过量预防站点 (OPS) 的关闭导致客户之间增加了阿片类药物激动剂治疗 (OAT) 的发行. 由于后续调查有限,对医疗保健使用和死亡率的短期影响仍然没有确定性.
科学领域:
- 公共卫生 公共卫生
- 成 药物 药物 药物 药物
- 医疗保健服务研究 医疗服务研究
背景情况:
- 关于监督药物消费服务 (SDC) 影响的证据,特别是在退出服务期间,是混合的.
- 很少有研究利用个人级别,可链接的健康数据来评估这些影响.
- 加拿大阿尔伯塔省的红鹿过量预防站 (OPS) 计划关闭,提供了一个独特的研究机会.
研究的目的:
- 为了检查在红鹿OPS关闭公告和终止后,在可识别的OPS客户中开放阿片类激素治疗 (OAT) 的变化.
- 评估这些客户急性医疗保健利用率和死亡率的变化.
主要方法:
- 使用链接的省级行政卫生数据进行回顾性队列研究.
- 分段差异中差异中断时间序列 (DID-ITS) 设计,将红鹿OPS客户与连续运营的莱斯布里奇OPS客户进行比较.
- 现场中断时间序列 (ITS) 模型仅用于红鹿的分析.
主要成果:
- 关闭后,红鹿客户在OAT上的比例增加,超过了莱斯布里奇客户的比例 (16.1%对14.4%,P < 0.021).
- 在急诊室访问或涉嫌阿片类药物相关的紧急医疗服务事件中没有观察到统计学上显著的差异.
- 死亡事件很少发生,在随访期间没有观察到统计学上可检测的增加.
结论:
- 红鹿OPS的关闭与其用户中OAT分发的增加有关.
- 对急性医疗利用率和死亡率的短期影响似乎稳定,但需要更长的随访才能获得确的结果.
- 个人健康数据对于评估SDC退出服务的影响至关重要.
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