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工程化CAR-T衍生的外基因组共同提供miR-145和细胞毒性蛋白质,用于向固体瘤治疗

Ruyue Yang1, Haitao Wang2, Guidan Wang1

  • 1Henan Key Laboratory of Microbiome and Esophageal Cancer Prevention and Treatment, The First Affiliated Hospital, College of Clinical Medicine, Henan University of Science and Technology, Luoyang, China.

Journal of extracellular vesicles
|March 10, 2026
PubMed
概括

来自载有miR-145 (exo-CT-145) 的CAR-T细胞的工程外体显示出对固体瘤治疗的希望. 这种无细胞疗法有效地向瘤,降低毒性,提供更安全,更有效的治疗方法.

关键词:
血管新生 血管新生仿真抗原受体T细胞的T细胞受体表皮介质介质过渡的表皮介质过渡.外基因组是外基因组的组成部分.微型RNA-1455 - - 这就是微型RNA-1455.消化管皮细胞癌的癌症.

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