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Updated: Mar 12, 2026

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设计,合成,体外和体内评估多功能胺素作为潜在的多目标导向抗炎剂

Asmaa Essam1, Nermine A Osman1, Moataz A Shaldam2

  • 1Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.

Bioorganic chemistry
|March 10, 2026
PubMed
概括

新的胺衍生物通过抑制循环氧基酶-2 (COX-2) 和5-氧基酶 (5-LOX) 来表现出强大的抗炎作用. 化合物6有效降低了互白素-6 (IL-6) 和活性氧物种 (ROS) 的产生,这表明它具有强大的抗炎功能.

关键词:
5-LOX 五个锁.在COX-2中,COX-2是最常见的.在IL-6的研究中,IL-6被认为是IL-6的基因.在状的中.皮里米丁是什么 皮里米丁是什么这就是ROSOS ROS.

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