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Updated: Mar 12, 2026

A Modified Technique for Transverse Aortic Constriction in Mice
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Published on: August 18, 2022

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修改后的hTERT治疗改善了压力过载引起的心力衰竭

Yinlong Zhao1, Xiaolu Bao1, Weiyao Xiong1

  • 1Department of Cardiology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200125, China; Shanghai Institute of Precision Medicine, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200125, China.

EBioMedicine
|March 10, 2026
PubMed
概括

使用修改的人类端粒酶 (modhTERT) 的基因疗法通过保护端粒来逆转小鼠的心力衰竭. 这种方法为心力衰竭患者提供了潜在的新疗法.

关键词:
对DNA损伤的反应反应心脏衰竭是因为心脏衰竭.线粒体中的线粒体.泰洛米尔 (Telomere) 是一种电离体.这就是hiPSC-CMs.

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