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Updated: Mar 12, 2026

Isolation and Quantitative Evaluation of Brush Cells from Mouse Tracheas
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S1P/S1PR3轴驱动了长期鼻炎与鼻的上皮功能障碍和2型炎症

Han Chen1, Lin Wang1, Lin Han2

  • 1Department of Otolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China; Shandong Provincial Engineering Research Center for Precision Diagnosis and Therapy in Otorhinolaryngology, Qingdao, Shandong, China; Qingdao Municipal Key Laboratory of Nasal Diseases, Qingdao, Shandong, China.

Mucosal immunology
|March 10, 2026
PubMed
概括

斯芬戈辛-1-酸盐 (S1P) /S1P受体 (S1PR) 轴,特别是S1PR3,驱动长表皮功能障碍和慢性鼻炎与鼻 (CRSwNP) 的2型炎症. 针对这一轴可能为CRSwNP提供新的治疗方法和生物标志物.

关键词:
生物标志物生物标志物慢性鼻炎与鼻多.皮质屏障是一种表皮屏障.皮质-介质细胞过渡.在S1PR3中使用.斯芬哥辛-1-酸盐是一种酸盐.这是一种2型炎症.

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