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Updated: Mar 12, 2026

Characterization at the Molecular Level using Robust Biochemical Approaches of a New Kinase Protein
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Characterization at the Molecular Level using Robust Biochemical Approaches of a New Kinase Protein

Published on: June 30, 2019

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CDKL5激酶经历液-液相分离,由富含氨酸的C终端区域驱动

Stefania Boggio Bozzo1, Marco Dell'Oca1, Serena Vaglietti1

  • 1Rita Levi-Montalcini Department of Neuroscience, University of Turin, Turin, Italy.

Life science alliance
|March 10, 2026
PubMed
概括

CDKL5蛋白激酶经历液体-液体相分离 (LLPS),由其C终端域驱动. 这个域的切断会损害LLPS和功能,可能有助于CDKL5缺乏障碍 (CDD) 的发病.

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