改变鼻科学,未知的流行病学:我们对社区中的功能神经系统障碍有什么了解?
O Mounir Alaoui1, E Roze2, A Daubigney3
1FND unit, Department of Neurology, FHU treat-FND, Hopital Avicenne, AP-HP, Bobigny, France; Sorbonne University, Paris, France.
Revue neurologique
|March 10, 2026
概括
这一系统性审查揭示了成人功能神经障碍 (FND) 的广泛流行和发病率. 迫切需要更多高质量的研究,以建立可靠的FND流行病学,以制定卫生政策.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 功能神经障碍 (FND) 存在因功能性而非结构性异常而导致的运动/感官症状.
- 尽管在神经病学中很常见,但FND的流行病学记录仍然很差.
- 了解FND的流行和发病率对于公共卫生规划至关重要.
研究的目的:
- 在一般人群中系统地审查和估计FND的流行病学.
- 评估有关FND流行和发病率的现有研究的质量.
- 发现FND流行病学中的研究缺口.
主要方法:
- 按照PRISMA指南进行系统的文献审查.
- 在PubMed和Embase搜索了有关成人FND发病率/流行率 (1972-2022) 的研究.
- 使用乔安娜·布里格斯研究所的流行临界评估工具评估研究质量.
主要成果:
- 包括27项研究,主要来自印度,美国和欧洲.
- 报告的FND患病率估计在每10万人口中从37.2到6900;发病率从10.7到186.
- 功能分离性和运动障碍的患病率和发病率各不相同;大多数病例涉及年轻女性. 只有8项研究是高质量的.
结论:
- 现有的FND流行病学数据因改变诊断标准而复杂化.
- 强调迫切需要对各种形式的FND进行大规模,严格的研究.
- 可靠的流行病学数据对于制定适当的FND健康政策至关重要.
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