激光辅助的氧化矿化用于牙管道封闭
Mingxing Li1, Kai Zhang1, Rong Bao1
1Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, Zhejiang, China.
概括
一种新的策略结合了氧化沉积和激光处理,以有效地阻塞牙管道. 这种方法可以控制牙过敏,提供抗酸性,并提供抗菌的好处.
科学领域:
- 生物材料科学是生物材料的科学.
- 牙科材料 牙科材料
- 纳米技术 纳米技术
背景情况:
- 牙过敏 (DH) 是由于牙管 (DTs) 暴露而引起的.
- 目前的治疗方法缺乏长期的疗效和抗酸性.
- 需要策略来封闭DTs,抵抗酸,并提供抗菌性质.
研究的目的:
- 开发一个协同策略,以有效和抗酸的牙管道 (DTs) 的阻塞.
- 通过将现场氧化沉积与激光照射相结合来管理牙过敏性 (DH).
- 为牙表面赋予抗菌活性.
主要方法:
- 一种"替代浸泡"方法将氧化沉积在非矿物化牙上.
- Nd:YAG激光照射将氧化转化为氧化,密封DTs.
- 鉴定包括SEM,TEM,EDX,FTIR,XRD,SAED,CFU试验和CCK-8试验.
主要成果:
- 通过氧化实现了原纤维的快速矿化.
- Nd:YAG激光照射有效地将氧化转化为氧化,包括DTs.
- 修改后的牙表现出耐酸性,对突变性链球菌具有显著的抗菌活性,并且具有出色的生物相容性.
结论:
- 交替浸泡和Nd:YAG激光照射的结合方法有效地矿化了非矿化牙.
- 这种方法提供了强大的牙管封闭,具有抗酸性和抗菌性.
- 这一策略显示出作为牙过敏症的新疗法的巨大潜力.
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