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Updated: Mar 12, 2026

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通过氧化脱硫来调节tRNA修饰的转化调节

Yufeng Mo1, Kensuke Ishiguro1,2, Kenjyo Miyauchi1

  • 1Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Japan.

Nature communications
|March 11, 2026
PubMed
概括

氧化应激可以改变转移RNA (tRNA) 的修饰,特别是xm5s2U到xm5h2U的脱硫. 这种修改会损害tRNA功能,影响人类和哺乳动物细胞中的蛋白质合成和密码子识别.

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