在接受抗风湿治疗的类风湿性关节炎患者中,口腔软组织的表现:范围审查
Beatriz Braga Tenório1, Laura Lemos da Silva de Souza1, Pedro Albuquerque Counago Marques1
1Department of Pathology and Oral Diagnosis, School of Dentistry, Universidade Federal do Rio de Janeiro, Professor Rodolpho Paulo Rocco, 325-Cidade Universitária da Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21941-617, Brazil.
Odontology
|March 11, 2026
概括
口腔软组织问题,如和口腔干燥,是类风湿性关节炎 (RA) 抗风湿药物的常见副作用. 专家的早期识别可以防止严重的后果.
科学领域:
- 口腔医学是指口腔医学.
- 类风湿病学 类风湿病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 类风湿性关节炎 (RA) 治疗包括抗风湿药物.
- 这些疗法可能会导致口腔软组织的表现.
- 这些表现的证据需要综合.
研究的目的:
- 审查和总结有关RA患者口腔软组织问题的证据.
- 识别临床模式,涉及的药物和知识差距.
主要方法:
- 使用多个数据库 (PubMed,Scopus,Web of Science,Embase,LILACS) 和灰色文献进行了范围审查.
- 包括观察性和干预性研究,评估与RA中抗风湿剂相关的口腔表现.
- 数据被提取并描述性地总结.
主要成果:
- 分析了14项涉及4446名RA患者的研究.
- 甲基是最常见的药物;口腔是最常见的表现 (9.13%),通常与甲基有关.
- 此外,还报告了 Xerostomia (1.95%) 和口腔炎 (0.6%),特别是在组合疗法时. 病变通常是轻微的.
结论:
- 口服表现是RA抗风湿治疗的显著,未被认可的不良影响.
- 风湿病学家和口腔医学专家之间的合作对于早期检测和管理至关重要.
- 改进的识别和诊断可以预防严重的口腔并发症.
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