在专家腹膜恶性病患者中,腹膜疾病评估的形态学和观察者间的变化SURGONS:MORPHEUS研究
Aditi Bhatt1, Vivekanand Sharma2, Ajinkya Pawar3
1Department of Surgical Oncology, Shalby Cancer and Research Institute, Shalby Hospital, Ahmedabad, India. aditimodi31@gmail.com.
Annals of surgical oncology
|March 11, 2026
概括
专家外科医生在评估腹病变时表现出显著的分歧,影响癌症的分期. 标准化术语和评分可以提高腹膜恶性瘤细胞还原性手术的一致性.
科学领域:
- 在瘤学瘤学.
- 手术病理学手术病理学
- 医疗成像医学成像
背景情况:
- 腹癌指数 (PCI) 对于分期腹恶性瘤至关重要.
- 准确地描述腹病变 (PLs) 对于治疗规划至关重要.
- 评估PLs的观察者间变异性可能会影响患者的治疗结果.
研究的目的:
- 分析观察者之间的变化,以分配病变得分 (LS),形态术语 (MT) 和恶性瘤的概率 (POM) 的PLs.
- 评估专家外科医生在从手术内图像中描述PLs方面的共识.
- 确定描述腹腔疾病的标准化潜在领域.
主要方法:
- 80张PLs的手术内图像由50名专家腹腔瘤恶性外科医生审查.
- 外科医生为每个图像分配了LS,选择了MT,并预测了POM.
- 使用Krippendorff的alpha (α) 评估了观察者之间的可靠性.
主要成果:
- 对于LS (22.5%,α = 0.174) 和MT (26.5%,α = 0.0902) 实现了较低的共识.
- 恶性瘤 (POM) 的概率仅在52.5%的病例 (α = 0.155) 中得到了准确的预测.
- 新辅助化疗没有影响外科医生的评估.
结论:
- 经验丰富的外科医生在描述PLs时存在很高的观察者间变化.
- 需要对MT进行标准化和对PL进行评分,以减少不一致.
- 德尔菲共识方法可以提高腹膜恶性瘤评估的一致性.
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