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在明尼苏达州有两例Erysipelothrix rhusiopathiae感染病例,2024年

Kelly E Schenk^1,2, Jeffrey Kubiak³, Jennifer L Dale²

¹Applied Epidemiology Fellowship, Council for State and Territorial Epidemiologists, Atlanta, Georgia, USA.

Zoonoses and public health

|March 11, 2026

概括

在明尼阿波利斯-圣保罗发生了两个罕见的Erysipelothrix rhusiopathiae感染. 调查没有发现疫情的联系或共同来源,这表明通过未煮熟的肉或受污染的表面可能暴露.

科学领域:

微生物学微生物学
传染性疾病传染性疾病
公共卫生流行病学流行病学

背景情况:

埃里西佩洛特里克斯 (Erysipelothrix rhusiopathiae) 在人类中引起感染,通常与职业暴露有关.
2024年7月,在明尼阿波利斯-圣保罗大都会地区发现了两例人类病例,引发了调查.
明尼苏达州卫生部 (MDH) 发起了一项研究,因为担心可能爆发疫情.

研究的目的:

调查Erysipelothrix rhusiopathiae感染的来源和潜在爆发情况.
确定这两个确诊病例的流行病学联系和遗传相关性.
确定与这些感染相关的潜在暴露途径和风险因素.

主要方法:

与病例患者的家属进行了流行病学访谈.
下一代测序是在MDH公共卫生实验室的细菌分离物上进行的.
查询了电子健康记录 (EHR),以确定其他病例.

主要成果:

这两名病例患者都是来自赫蒙族社区的成年人,有潜在的健康状况.
潜在的暴露包括原料或未煮熟的肉,可能来自活动物市场.
细菌分离物显示出显著的遗传差异 (23,328个单核酸多态),并且在EHR中没有发现其他病例.

结论:

由于缺乏流行病学联系和遗传相关性,这两个病例被认为不太可能是疫情爆发的一部分.
潜在的感染源包括不充分煮熟的肉类消费或环境接触受污染的生肉.
建议对罕见的Erysipelothrix rhusiopathiae病例进行进一步研究,以建立未来疫情调查的证据.

关键词:

流行病学流行病学疫情爆发的原因是公共卫生实践公共卫生实践

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