维生素D缺乏和手术部位感染的风险:一个系统的审查和元分析协议
Rana Farsakoury1,2, Habib H Farooqui1, Susu M Zughaier3
1College of Medicine, QU Health, Qatar University, Doha, Qatar.
Systematic reviews
|March 11, 2026
概括
维生素D缺乏可能会增加手术部位感染 (SSI) 的风险. 本系统性审查和元分析评估了维生素D水平与SSI发展之间的联系,以告知潜在的干预措施.
科学领域:
- 传染性疾病 传染性疾病
- 营养科学 营养科学
- 外科手术的结果
背景情况:
- 维生素D可能具有间接的抗微生物特性.
- 现有文献表明,维生素D与减少感染风险之间存在潜在联系.
- 手术部位感染 (SSIs) 代表了医疗保健的重大负担.
研究的目的:
- 系统地评估维生素D缺乏与发展SSI的风险之间的联系.
- 对所有相关研究进行全面的元分析,无论语言如何.
- 澄清维生素D在SSI发展中的作用.
主要方法:
- 系统审查和元分析,包括所有类型的研究.
- 进行广泛的数据库搜索 (Medline,Embase,Cochrane等) 在2025年12月之前.
- 根据PRISMA标准进行研究选择;使用偏差调整方法进行元分析.
- 通过MASTER尺度对偏见风险的评估,通过GRADE框架对证据的确定性.
主要成果:
- 这项研究旨在确定维生素D缺乏是否是SSI的重要风险因素.
- 结果将量化维生素D水平与SSI发病率之间的关联.
- 审查将提供当前证据的全面概述.
结论:
- 维生素D在SSI风险中的作用需要进一步阐明.
- 建立一个协会可以支持手术前的维生素D查和优化.
- 这可能会减少SSI的发生率和负担.
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