自主指导的高强度间隔与适度持续训练对心脏代谢健康在代谢功能障碍相关的稳态性肝病:一个随机对照试验
Ping-Lun Hsieh1,2, Chun-Jen Liu3,4, Chih-Horng Wu5
1School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan.
Scandinavian journal of medicine & science in sports
|March 11, 2026
概括
高强度间歇训练 (HIIT) 和中等强度持续训练 (MCT) 在代谢功能障碍相关的脂肪性肝病 (MASLD) 中同样减少肝脂肪. HIIT提供了卓越的心肺呼吸系统健身改善.
科学领域:
- 运动生理学 运动生理学
- 肝病学 肝病学是一种肝病学.
- 心血管健康 呼吸系统健康
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 管理指南建议运动.
- 对于MASLD患者来说,最佳的运动方式仍未确定.
- 以前的研究没有直接比较HIIT和MCT对MASLD心肺和肝脏脂肪的结果.
研究的目的:
- 为了比较高强度间歇训练 (HIIT) 与中等强度持续训练 (MCT) 对MASLD患者的心肺健康和肝硬化症的影响.
- 为了确定运动强度是否影响MASLD患者的肝脂肪减少.
- 评估不同运动模式对代谢参数的影响.
主要方法:
- 一项随机试验,涉及超声波确认的MASLD (以前称为NAFLD) 患者.
- 参与者被分配到24周的HIIT (n=46) 或MCT (n=49),每周三次在自由生活环境中进行跑步机训练.
- 一个非随机观察组 (OBS; n=20) 被纳入用于比较. HIIT需要5个周期,每隔4分钟,在80%-90%的峰值氧气消耗 (V·O2峰值) 时,恢复3分钟,而MCT需要30-40分钟,在60%的V·O2峰值时.
主要成果:
- 与OBS组相比,HIIT和MCT都显著降低了肝肥胖症 (p <0.05),运动方式之间没有显著差异.
- 与MCT和OBS (p <0.05) 相比,HIIT在峰值氧气消耗 (V·O2峰值) 中表现出显著更大的改善.
- 两个运动组都在中度至高强度下增加了每分钟通风和碳水化合物利用率,而不是OBS (p < 0.05).
结论:
- 运动参与,而不是强度,似乎是减少MASLD肝脏脂肪的主要驱动因素.
- 与MCT相比,HIIT在改善MASLD患者的心肺健康方面提供了卓越的好处.
- 无论是HIIT还是MCT都有效降低肝硬化症,这凸显了定期体育活动对MASLD管理的重要性.
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