相关实验视频

Updated: Mar 12, 2026

Measurement and Analysis of Extracellular Acid Production to Determine Glycolytic Rate
06:47

Measurement and Analysis of Extracellular Acid Production to Determine Glycolytic Rate

Published on: December 12, 2015

25.9K

双碳酸盐和其他缓冲疗法在急性代谢酸症:一个系统的审查和元分析

Peter C Lind1,2,3, Frederik G Hansen1,2, Mathias J Holmberg1,2

  • 1Department of Anaesthesiology and Intensive Care, Aarhus University Hospital, Aarhus, Denmark.

Acta anaesthesiologica Scandinavica
|March 11, 2026
PubMed
概括

在急性损伤的ICU患者中,急性代谢酸化的缓冲疗法可能会减少替代疗法的使用,但可能不会改善存活率. 对于心脏骤停,生存结果没有得到改善.

更多相关视频

Establishment of an Extracellular Acidic pH Culture System09:41

Establishment of an Extracellular Acidic pH Culture System

Published on: November 19, 2017

15.5K
Simultaneous pH Measurement in Endocytic and Cytosolic Compartments in Living Cells using Confocal Microscopy09:46

Simultaneous pH Measurement in Endocytic and Cytosolic Compartments in Living Cells using Confocal Microscopy

Published on: April 28, 2014

15.7K

相关概念视频

Bicarbonate-Carbonic Acid Buffer01:22

Bicarbonate-Carbonic Acid Buffer

The carbonic acid-bicarbonate buffer system is critical for maintaining the body's pH balance. It operates on the equilibrium:
7.1K
Diagnosing Acidosis and Alkalosis01:24

Diagnosing Acidosis and Alkalosis

Diagnosing acid-base imbalances involves systematically analyzing arterial blood samples, focusing on three key measurements: pH, bicarbonate (HCO3−) concentration, and carbon dioxide partial pressure (PCO2). This analysis follows a four-step process that helps identify the imbalance's underlying cause and nature.
First, the pH level is assessed to determine whether the blood pH is normal (7.35–7.45), low (acidosis), or high (alkalosis).
Next, the PCO2  and...
1.5K
Buffer Systems in the Body01:19

Buffer Systems in the Body

Chemical buffers play a critical role in the body's regulation of pH levels. These systems contain one or more compounds that stabilize pH changes by neutralizing strong acids or bases. When pH levels drop, hydrogen ions bind to a weak base; when pH levels rise, hydrogen ions are released. This dynamic process helps maintain pH within a narrow and stable range essential for normal physiological function.
A typical buffer system in bodily fluids includes a weak acid and its corresponding...
5.0K
Renal Regulation of Acid-Base Balance01:29

Renal Regulation of Acid-Base Balance

Metabolic reactions in the body produce nonvolatile acids, such as sulfuric acid, which generate an acid load of approximately 1 mEq of H+ per kilogram of body weight daily. Excreting H+ in the urine is essential to balance this acid load.
In the kidneys, cells within the proximal convoluted tubules (PCT) and the collecting ducts secrete hydrogen ions (H+) into the tubular fluid. Specifically, in the PCT, Na+/H+ antiporters secrete H+ while reabsorbing Na+.
However, the intercalated cells in...
2.1K
Acid-Base Balance01:25

Acid-Base Balance

The human body maintains a narrow pH range regulated through acid-base balance. This balance is crucial as changes in the hydrogen ion concentration can disrupt cell membrane stability, alter protein structures, and change enzyme activities. The normal pH of arterial blood is 7.4, venous blood and interstitial fluid is 7.35, and intracellular fluid averages 7.0.
When the pH of arterial blood rises above 7.45, it results in a condition called alkalosis. Conversely, a drop below 7.35 leads to...
2.9K
Compensation Mechanisms01:28

Compensation Mechanisms

The human body employs intricate mechanisms to counteract changes in blood pH, preventing conditions like acidosis (pH < 7.35) and alkalosis (pH > 7.45). These compensatory responses aim to restore normal arterial blood pH by engaging respiratory or renal systems, depending on the source of the imbalance.
Respiratory Compensation
This mechanism addresses metabolic-induced pH imbalances by adjusting breathing rates. Respiratory compensation begins within minutes of detecting a pH...
2.4K