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人类严重创伤性脑损伤中围组织的转录形状

Adaliana Sorg Mousessian Onohara1, Sueli Mieko Oba-Shinjo1, Vitor Nagai Yamaki2

  • 1Department of Neurology, Faculdade de Medicina, Laboratory of Molecular and Cellular Biology (LIM15), Universidade de Sao Paulo, Sao Paulo, SP, Brazil.

Journal of neurotrauma
|March 11, 2026
PubMed
概括

创伤性脑损伤 (TBI) 引发炎症并改变基因表达,影响大脑细胞功能. 这项研究确定了关键信号通路和CCL2-SPHK1轴,为TBI治疗提供了潜在的治疗点.

关键词:
人类 人类 人类 人类 人类 人类 人类周周结组织组织.信号通道的信号通道.转录组分析转录组分析创伤性脑损伤是一种创伤性脑损伤

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Traumatic Brain Injury l: Introduction01:28

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DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...
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