SARS-CoV-2测试对初级保健水平上寻求医疗保健行为的影响
Cheyenne C E van Hagen1, Eric R A Vos1, Charlotte Lanièce Delaunay2
1Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
International journal of epidemiology
|March 11, 2026
概括
COVID-19自我测试可能会偏见疫苗有效性研究. 在荷兰,在接种疫苗的个体中,自我测试更为常见,但无论是自我测试还是接种疫苗都没有影响全科医生访问,这表明疫苗有效性研究中的潜在选择偏见.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染病研究 传染病研究
背景情况:
- 对SARS-CoV-2的诊断性自我测试可以在COVID-19疫苗有效性 (VE) 研究的测试负面设计 (TND) 中引入选择偏差.
- 这种偏见在初级保健层面尤为重要.
研究的目的:
- 为了研究SARS-CoV-2自我检测和在荷兰一般人口中寻求初级保健医疗服务之间的关联.
- 评估从TND获得的COVID-19疫苗有效性估计中的潜在选择偏差.
主要方法:
- 利用PIENTER冠状病毒队列研究 (2022年6月至2023年4月) 的聚合问卷数据.
- 包括3152名18岁以上的参与者报告急性呼吸道感染 (ARI).
- 采用了根据人口统计和临床因素调整的日志双项回归分析.
主要成果:
- 接种了ARI疫苗的个人更有可能对SARS-CoV-2进行自我测试 (aRR 1.13).
- 疫苗接种情况和整体自我测试结果都没有与全科医生咨询有显著的关联.
- 然而,趋势表明接种疫苗的个体不太可能,未接种疫苗的个体更有可能在积极的自我测试后咨询全科医生.
结论:
- 2022年3月至2023年5月期间,荷兰人口的全科医生咨询可能因自我测试结果和疫苗接种情况而有所不同.
- 这表明,使用依赖于咨询前测试的TND方法,在COVID-19 VE估计中可能存在选择偏差.
- 建议在不同的环境中进行进一步的研究,以验证这些发现.
更多相关视频
相关概念视频
Preventive Healthcare Services
2.3K
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
2.3K
Primary Healthcare Services
2.6K
Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
2.6K
Secondary Healthcare System
2.1K
Secondary healthcare is offered by a specialist, generally in hospitals or clinics for patients referred by primary healthcare providers. It occurs when a person has an illness or injury that requires specific medical care. Secondary care is often referred to as acute care. Secondary care can range from uncomplicated care to repair a minor laceration or treat a strep throat infection to more complicated emergent care, such as treating a head injury sustained in an automobile accident. Whatever...
2.1K
Healthcare Associated Infections II: Preventive Measures
4.6K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
4.6K
Factors Affecting Illness
5.6K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
For instance, risk factors are connected to illness,...
5.6K
Sensitivity, Specificity, and Predicted Value
1.6K
In healthcare diagnostics, laboratory tests play a crucial role in identifying and diagnosing a wide range of medical conditions. However, interpreting test results is not always straightforward. An abnormal test result does not always confirm the presence of a disease, just as a normal result does not guarantee its absence. To assess the reliability of these diagnostic tools, healthcare practitioners rely on two key statistical indicators: sensitivity and specificity.
Sensitivity is the...
Sensitivity is the...
1.6K


